Interestingly, only cell death caused by atorvastatin can be restrained by the treatment with ferroptosis inhibitor, such as DFO (Figures 1B,F), Fer-1 (Figures 1C,G) and Lip-1 (Figures 1D,H), while cell death caused by lovastatin cannot be rescued by Fer-1 in HCM and C2C12 (Supplementary Figures S2A,B)
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Gastrointestinal side effects were similar, though discontinuation rates were high for both drugs
Troches are small dissolvable lozenges that sit in your mouth until they melt, slowly releasing medication through the lining of your cheek or under your tongue