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2025;64(44):e202509183
Gastrointestinal side effects are the most commonly reported and include: Nausea (affecting 1040% of patients, depending on the specific GLP-1 agonist) Vomiting and diarrhoea (less common than nausea but can contribute to dehydration) Constipation (due to slowed gastric emptying) Abdominal discomfort or bloating These effects are typically most pronounced during treatment initiation and following dose increases
2g, h, Table 1)
Severe nausea, vomiting, inability to eat, extreme fatigue, or persistent digestive distress suggest the dose may be too high
It physically tightens the gaps between the cells in your intestinal lining
