Possible reasons include Type 1 diabetes diagnosis, advanced Type 2 diabetes with severely depleted beta cells, contraindication to GLP-1 drugs (thyroid cancer history, pancreatitis history), insurance or cost barriers, prior GLP-1 intolerance, or very high blood sugar requiring immediate insulin coverage
Worse, some pharmacies compound at 10 mg/mL or higher
Other GLP-1R populations in the ACB, LSc, PVH, lateral hypothalamus (LHA), and VTA are involved in food choice, reward, and taste aversion (2125)
Somun, D
Jing-Jing Cardona Sep 27, 2024 4 min read Updated: Feb 5 Semaglutide and tirzepatide have become prominent in weight loss and diabetes management due to their proven effectiveness