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This single center, one-year trial enrolled 97 children with T1D within 6 weeks of diagnosis (NCT02002130)
Oral supplements act systemically and may support antioxidant balance and pigment regulation pathways over time
Histological examination of skin sections with hematoxylineosin and Masson staining showed better granulation tissue formation, reepithelialization, dermal remodeling, and a higher extent of collagen deposition when compared to the model control group on the 18th day postwounding
One published case series (N=14 patients, mixed athletic backgrounds) noted that 11 of 14 participants reported reduced DOMS duration from an average of 72 hours to approximately 36 hours, though this was self-reported and uncontrolled
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