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Moreover, there have been hypoglycemic agents such as SGLT-is have been proven to have direct renal benefits independent of glucose

However, Etomoxir lacks selectivity to CPT1 isoforms, and TDGA can affect the renin angiotensin system, resulting in myocardial hypertrophy and other side effects (Selby and Sherratt, 1989)

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(1) Observed mean value from Week 0 to Week 40, and (2) least-squares mean standard error at Week 40 multiple imputation (MI)