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The key diagnostic element of chronic ACM is LV dysfunction in the setting of longstanding alcohol use and the absence of CAD

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In the recent European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD), European Association for the Study of Obesity (EASO) clinical practice guidelines on the management of MASLD it was also stated that PIO can be used safely in individuals with non-cirrhotic MASH [6]

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