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The most common side effects are gastrointestinal: nausea, diarrhea, constipation, and reduced appetite
Patients who lose weight slowly through dietary restriction alone rarely report the same level of fatigue or 'brain fog' that some tirzepatide users describe in weeks 410 of therapy, and this subjective difference may reflect the pace at which their antioxidant systems are being challenged
J Translational Med
Symptoms That May Prompt Additional Testing While some side effects are typical with GLP-1 use nausea, vomiting, constipation, diarrhea, bloating, and heartburn, for example others may prompt immediate medical attention