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Similarly, the appetite-suppressing effects of liraglutide have been traced to its action within the arcuate nucleus (ARC) of the hypothalamus, a region also characterized by a relatively permeable BBB (Secher et al., 2014)

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There was no history of bleeding, pain, induration or sudden enlargement of that lesion

chronically, it upregulates beta-3 adrenergic receptor (3-AR) expression in adipose tissue (restoring levels to lean-equivalent) to sustain fat oxidation

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