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This paradigm shift would expand the conceptual framework of addiction treatment beyond dopamine-centric models and open new avenues for addressing other substance use disorders, including alcohol, stimulants, and nicotine
These executive processes are dependent on the prefrontal cortex ( PFC ) of rodents and humans, an area that is substantially vulnerable to TBI 8,9
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Strategies aimed at ROS generation Inhibitors of ROS production, including NOX inhibitors, mitochondrial ROS inhibitors, monoamine oxidase inhibitors, XO inhibitors, and NOS inhibitors, all have higher specificity [440]
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