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Footnote Nonstandard Abbreviations and Acronyms 2-NBDG 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amino)-2-deoxyglucose Cas9 clustered regularly interspaced short palindromic repeatassociated 9 CRISPR/Cas9 clustered regularly interspaced short palindromic repeats/clustered regularly interspaced short palindromic repeatassociated 9 DAPI 4,6-diamidino-2-phenylindole DPP-4 dipeptidyl peptidase-4 EC endothelial cell eNOS endothelial NO synthase EPC endothelial progenitor cell FBS fetal bovine serum GLP-1 glucagon-like peptide 1 GLP-1R glucagon-like peptide 1 receptor HG high glucose HLI hind limb ischemia HRP horseradish peroxidase hUCB-EPC human umbilical cord bloodderived EPC HUVEC human umbilical vein endothelial cell INS-1 insulinoma 1 KLF2 Kruppel-like factor 2 LDHA lactate dehydrogenase A mEPC mouse primary bone marrow EPC mBM-EPC mouse bone marrowderived EPC NEP 24.11 neutral endopeptidase 24.11 OCR oxygen consumption rate PAD peripheral artery disease PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 PKA protein kinase A PKG protein kinase G ROS reactive oxygen species T1DM type 1 diabetes UEA-1 ulex europaeus agglutinin-1 WT wild type Supplemental Material File (atvb_atvb-2024-320714d_supp1.pdf) Download 5.37 MB File (atvb_atvb-2024-320714d_supp2.pdf) Download 22.54 MB REFERENCES 1

Convert the dose to micrograms before calculating injection volume to avoid unit mismatch

CVS Caremark chose Wegovy (semaglutide) over Zepbound (tirzepatide) as its covered weight loss medication

However, he says that as Ozempic starts to improve insulin resistance, sleep quality should also improve

Many of our patients report constant, daily frustration of religiously counting calories, sweating through intense workouts, and still the numbers on the scale refuse to budge