Focus on four key priorities: Protein: 100-150 grams daily Fiber: 25-35 grams daily Water: 80-120 ounces daily Carbohydrates: Primarily from whole-food sources When combined with healthy habits, strength training, adequate sleep, and consistent medication use, this approach can help maximize weight loss while supporting long-term health and sustainability
To ensure progress, we monitor body composition using monthly Styku 3D body scans , allowing us to adjust your plan as your body responds
Increase fullness signals so patients need less food to feel satisfied
Diab Care 36 , 13961405 (2013)
Time period What may be noticeable What the evidence supports Weeks 1-4 Satiety, appetite changes, nausea, bowel changes, early scale movement Early tolerability period, not the main efficacy endpoint window Weeks 4-12 More consistent appetite suppression and early weight trend Direction of response may become clearer, but individual variance is high Weeks 12-24 Clinically meaningful separation becomes easier to evaluate Phase 2 primary endpoint at 24 weeks showed dose-dependent weight loss Weeks 24-48 Major body-weight reduction window in Phase 2 48-week Phase 2 secondary endpoint showed the largest published Phase 2 changes Weeks 68-104 Longer-term Phase 3 and extension outcomes TRIUMPH program endpoints measure durability over longer windows Weeks 1-4: Early Signals, Not Final Results The first few weeks are usually the wrong window for judging full retatrutide results