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Previous reports that megadoses of vitamin C destroy vitamin B 12 have not been supported (147) and may have been an artifact of the assay used to measure vitamin B 12 status (21)

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Oxidative metabolism signatures predict response to 5FU-based chemotherapy treatment Given this robust adaptation to facilitate cellular survival in cancer cells treated with 5FU, we next postulated that elevated mitochondrial metabolism may be a predictor of response to 5FU-based chemotherapy

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