CagriSema FDA approval timeline Novo Nordisk submitted the New Drug Application (NDA) to the FDA on December 18, 2025 , for chronic weight management in adults with obesity or overweight with a weight-related comorbidity
Thymosin beta-4 (often written as T4 or TB4) is a naturally occurring peptide, and TB-500 (or fequesetide) is a synthetic peptide based on a segment of TB4.3 4 While TB4 is made up of 43 amino acids, TB-500 contains only seven.4 5 Sometimes, especially in earlier research, you may see TB-500 referred to by its amino acid sequence, Ac-LKKTETQ.6 Insider Tip: The Ac- before amino acid sequences, like those of peptides, means its been permanently modified with an added acetyl group a process called N-terminal acetylation to protect it from degradation.7 8 This can improve a peptides stability,9 bioavailability,10 and other properties.11 Though nearly all synthetic peptides are protected in one way or another during synthesis, this protection is usually reversible
Transient use of a systemic adenosine kinase inhibitor attenuates epilepsy development in mice
GHK-Cu, also known as copper peptide, is a naturally occurring compound that plays an important role in skin renewal
Central melanocortin receptor (MC4R) agonism influences neural circuits of desire and arousal
