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This is the metabolic-rate component community framing is that glucagon agonism is why retatrutide produces weight loss numbers no GLP-1/GIP-only compound has matched
The glucagon arm appears to contribute substantively to body-composition outcomes (favouring fat-mass reduction) without offsetting the glycemic outcomes of the GLP-1/GIP arms (PMID 39515565, PMID 40609566)
In my world, thats more than enough evidence upon which a solid protocol can be built
However, high concentrations also increase the risk of aggregation
L-carnitine helps reduce overall body fat, including visceral fat around the midsection
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