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The same 2g administered intravenously or via intramuscular/subcutaneous injection delivers close to 100% systemically At 500mg/ml, a single 2ml injection of Dragon Pharma L-Carnitine delivers 1,000mg with near-complete bioavailability equivalent to approximately 5,500-7,000mg of oral L-Carnitine supplement in terms of what reaches the bloodstream This bioavailability advantage is particularly relevant for the androgen receptor upregulation application (below), where plasma L-Carnitine concentrations not gut absorption determine the effect How L-Carnitine Works The CPT Shuttle Mechanism L-Carnitine's primary metabolic function is a specific and elegant transport mechanism that most competitor content reduces to "moves fat to mitochondria": Long-chain fatty acids (the primary fat fuel for aerobic metabolism) cannot cross the inner mitochondrial membrane directly they require a specific transport system L-Carnitine acts as the shuttle carrier in the carnitine palmitoyltransferase (CPT) system : CPT1 on the outer mitochondrial membrane conjugates L-Carnitine to the fatty acid (forming acylcarnitine)

cinerea that resulted in an increased biosynthesis of secondary metabolites involved in plant defense

Cardiovascular Health: B12 works with other B vitamins to lower homocysteine, an amino acid that, at high levels, increases the risk of heart disease

Figure 4 and Additional file 1: Table S5 show the overall effects of the three classes of drugs on cardiorenal endpoints by the network meta-analysis using the frequentist approach

IDrugs Investig Drugs J (2009) 12:50313