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The spacial resolution of a bottom-up HDX experiment is limited by the generation and detection of peptides from pepsin proteolysis

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Tippairote, T., Hoonkaew, P., Suksawang, A

Key objectives include determining long-term safety, identifying patient subgroups most likely to benefit, clarifying effects across HF phenotypes, and assessing patient-centered outcomes such as quality of life, functional status, and hospitalization burden