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The thalamus receives direct input from the trigeminovascular system during every migraine attack and may therefore be subject to greater cumulative oxidative stress than cortical regions less directly involved in pain processing

The Vitamin C present in the capsules helps in giving antioxidants and nutrients to the skin and suppresses the melanin growth which increases the glow of the skin with the help of collagen production

Understanding how each medication functions is essential when considering their combined use

For patients not responding adequately at 12 weeks on a stable maintenance dose, clinicians should verify proper administration technique, assess adherence patterns, and consider whether further dose escalation is appropriate and tolerable before concluding the medication is ineffective

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