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Findings were categorized into motor symptoms (such as gait disturbances and neuropathy), non-motor symptoms (focusing on cognitive decline), pathophysiological mechanisms (based on molecular pathways, neuropathology, metabolites and genes), and therapeutic implications (Vit B12 supplementation, clinical recommendations)

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Prior to this modern development, liposuction was the only successful way to eliminate stubborn fat effectively and safely without requiring patients to also embrace an exercise and diet program

Investigations typically focus on pathway-level changes in lipid mobilization, intracellular lipid accumulation, and gene or protein expression patterns associated with metabolic regulation