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Both GLP1-RAs and SGLT2is contribute to weight loss through different mechanisms

These include direct cardiac effects (protection against myocardial ischaemia, reduction of epicardial adipose tissue and improvement of cardiac contractility), vascular (vasodilator effect and improvement of endothelial dysfunction), renal (reduced glomerular filtration rate and proteinuria drop) and metabolic (blood pressure decreased, lipid profile improved and glucose-lowering effect) (11)

Even two days per week of compound resistance movements, squats, deadlifts, rows, presses, provides meaningful muscle preservation stimulus

After removing the needle, discard the empty pen in a sharps container or household waste

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