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Regular screenings, dietary adjustments, and supplementing with B12 shots or pills can help manage and prevent deficiency

Both these methylation reactions are vital for growth and cell reproduction.[9][10] Methionine, a sulfur-containing, essential amino acid, is a precursor of S-adenosylmethionine, a cofactor for one-carbon metabolism and the final methyl donor for the methylation of DNA, RNA, proteins, and phospholipids.[11] The methionine synthase plays a paramount role in the synthesis of nitrogenous bases (purines and pyrimidines) involved in the formation of DNA

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At the same time, this may result in an imbalance of bile acids in the gut and liver and/or gallbladder dysfunction (since bile acids must be recycled)