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One study utilized chitosan nanoparticles, a biocompatible and biodegradable polymer, as a carrier for doxorubicin and AOD 9604
Potency loss isnt visible, which is why adhering to storage timelines is critical
More significant structural improvements reduced fine lines, improved firmness, better skin density typically become visible between weeks 8 and 12, with continued improvement through months 4 to 6 as collagen remodeling matures
Open questions include tissue-selective delivery, chronic dosing effects on one-carbon metabolism, and interactions with NAD precursor strategies [14,8,9]