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Emerging evidence demonstrates that miRNAs are critical regulators of lipid synthesis and FAO 81 resulting in defective cell metabolism and carcinogenesis 82 directly targeting key enzymes or transcription factors as oncogenes and tumor suppressors 81 as shown in Table 1

SpaMTPs network analysis results also revealed a chrome indole metabolite, D-dopachrome, which is potentially formed by oxidation of dopamine when exposed to oxidative stress, known to be associated with neurological disorders

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