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Notably, the expression of VDRs was significantly downregulated by the natural occurrence of AFB 1 (at nM concentrations) in osteosarcoma cell line SaOs-2

Emerging evidence underscores the centrality of FA metabolism perturbations in driving disease progression, from hyperuricemia-triggered crystal deposition to sustained NLRP3 inflammasome activation, ultimately forming a self-perpetuating metabolism-immunity axis

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The smaller volume keeps higher doses comfortably above 10 units