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doi: 10.1002/prca.201600169 60 HeLWongCKCheungKKYauHCFuAZhaoHLet al

Sermorelin was originally approved by the FDA in 1997 for treating growth hormone deficiency in children, but was discontinued in 2008 due to manufacturing issues, not safety concerns

However, it is also possible that melanoma precursor cells originate from mature melanocytes in the basal cell layer of the epithelium that have undergone dedifferentiation following cytogenetic alterations or from immature melanocytes/naevomelanocytes arrested in the submucosa during migration from the neural crest which for reasons unknown have acquired a malignant phenotype [15]

Common injection site reactions are characterized by itching and burning at the site of administration with or without thickening of the skin (welting)

The reasons align with everything discussed in this guide: better evidence, more consistent results, predictable dosing, and proven clinical trial backing