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Semaglutide is the established gold standard with FDA approval, proven cardiovascular benefit, extensive clinical data, and multiple formulation options

If Sejaro in the pen injector looks not like a colourless clear solution, then do not use it

Jardiance and GLP-1s are the rowboat and the speedboat of metabolic medication

[2] Romero MJ et al

Besides the already discussed actions of IGF-1 on glucose, it also has an indirect glucose-lowering effect secondary to its ability in increasing FA oxidation in muscle (will be further discussed in detail within the IGF - 1 and lipid metabolism section)