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FOXO4-DRI vs nearby senolytics Option FOXO4-DRI Type D-retro-inverso peptide Human trial stage None (preclinical only) Option Dasatinib + Quercetin (D+Q) Type Small-molecule drug + flavonoid Human trial stage Early human trials (e.g., Alzheimer's) Option Navitoclax Type BCL-2 family inhibitor Human trial stage Later-stage trials (e.g., myelofibrosis) D+Q and navitoclax are further along in humans but can affect healthy cells (e.g., low platelets)

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Detox supplements are promoted for removing toxins such as heavy metals from the body, but does research support their use and are such supplements safe

2009 Feb-Apr;30(1-2):1-12

At week 5, the dosage is typically raised to 5 mg once a week for another 4 weeks