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Its administration resulted in improved behavioral scores, reduced visceral hypersensitivity, and decreased intestinal inflammation, suggesting that triptolide modulates the gut-brain axis and inflammation in tandem

Combining these approaches with 5-amino-1mq could theoretically produce enhanced effects on cellular energy and fat metabolism

2013 Nov;10(11):2790-7

These findings similarly indicated that SFN and CDDO effectively reversed the expression levels of Nrf2 and NQO1 proteins, suggesting that HT-induced ferroptosis in colorectal cancer is linked to the suppression of the Nrf2 signaling pathway