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Berberine dosing in clinical studies typically ranges from 900-1500 mg daily, divided into two or three doses with meals to improve absorption and reduce gastrointestinal side effects

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Discussion This study provides support for the hypothesis that ketamine administration leads to acute increases in glutamatergic activity in the ACC in individuals with depression and that pretreatment with the opioid receptor antagonist naltrexone attenuates this increase

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Sometimes I'll go an extra day or two between injections but so far my limit is 48 hours and at that I feel my best

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