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One of the primary outcomes assessed was motor coordination and balance using the rotarod test

The molecular origin itself is a huge differentiator in the GHK-Cu vs KLOW analysis

Folinic acid (2 mg/kg/day, max 50 mg/day) produced significantly greater improvements in standardized verbal communication scores and several adaptive and behavioral subscales compared with placebo, with a stronger effect on children ( Furthermore, a placebo-controlled randomized trial evaluated the efficacy of folinic acid (5 mg twice daily) for 12 weeks in 19 children aged 310 years (sex distribution not reported) with ASD diagnosed by ADOS, without genetic syndromes, major medical comorbidities, or treatments affecting folate metabolism

Second: the short plasma half-life (~30 min) was insufficient, by the time the fragment circulating in the blood was supposed to act, it had already been metabolized

KD, Knockdown