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AFs and pathogenesis of Alzheimer's disease According to WHO statistics (231), there are more than 50 million AD-affected people worldwide such the statistics that have projected to increase by 2050 (187, 232)

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Data and materials availability Upon request, and subject to certain criteria, conditions, and exceptions (see for more information), Pfizer will provide access to individual de-identified participant data from Pfizer-sponsored global interventional clinical studies conducted for medicines, vaccines and medical devices (1) for indications that have been approved in the US and/or EU or (2) in programs that have been terminated (i.e., development for all indications has been discontinued)