Stimulants work to reduce your appetite and increase the number of calories that you burn at baseline (your metabolism)
Kreymann, B., Williams, G., Ghatei, M
Carnitine has been shown to be an endogenous substance with anti-inflammatory properties [47], as it inhibits the activity of NF-B and other core transcription factors involved in the inflammatory response and effectively reduces the levels of proinflammatory cytokines (e.g., IL-1, IL-6, and TNF-) [48, 49]
The fact that both approaches appear to enhance weight loss beyond GLP-1 agonism alone suggests that modulating GIP activity in either direction may be beneficial, potentially through different downstream mechanisms
investigated the pathogenic mechanisms of hormones in adipose tissue, which are linked to lipid dysregulation and the development of atherosclerosis (56)