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28 , 866875.e865 (2021)
A one-week titration at 1 mg may improve tolerability before advancing to the full 2 mg dose
In cancer, inducers of ferroptosis, such as erastin and RSL3, take advantage of the high levels of iron and PUFAs in tumor cells [94, 95], while inhibitors like fer-1 and liproxstatin-1 show potential in treating neurodegenerative diseases, including Alzheimers, where lipid peroxidation contributes to neuronal damage [96]
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