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A comprehensive meta-analysis published in 2017 examining data from over 60,000 patients found no significant increase in pancreatic cancer risk associated with GLP-1 receptor agonist use

Following a thorough analysis of our previous Phase IIb data and trial design, we are confident that with the preferred modified release formulation and optimized future trial design, we can advance a competitive oral GLP-1 molecule into registration-enabling studies to meet the ongoing medical needs of people living with obesity. The ongoing open-label, randomized study is assessing the pharmacokinetics and safety of immediate- and modified-release formulations of danuglipron administered orally in healthy adults aged 18 years or older

doi: 10.1080/10408398.2024.2317877 179

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