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These could range from pharmacotherapies targeting specific taste receptors (e.g., TAS2R agonists) to chrono-nutritional strategies and neuromodulation techniques designed to restore healthy signaling in pathological states

We highlight the role of novel therapies distinct from the gutkidney axis, including non-steroidal mineralocorticoid receptor antagonists (nsMRAs)

It works primarily on the vascular system , promoting blood flow and reducing inflammation

This conservative approach allows for gradual cellular adaptation while minimizing the potential for excessive detoxification responses

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