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Tirzepatide, especially at its higher doses, has been associated with slightly higher rates of nausea, vomiting, and diarrhea compared to semaglutide in some studies

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Generally, t 1/2 values of peptide drugs range from a few minutes to an hour ( The radioisotope probe assay is a cost-effective and fast method for generating informative data for early preclinical/pharmacokinetic absorption, digestion, metabolism, and excretion studies of biotherapeutics ( Determination of metabolites was the most challenging aspect of this study

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