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Additional materials may also be reviewed through broader internal catalog structures such as Research Compounds

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Some patients use GLP-1 medications for several months to reach their goal weight, then transition to a maintenance plan

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Mechanism of Action GLP-1 receptor agonists work through several complementary pathways: Enhanced insulin secretion : They stimulate the pancreas to release insulin in response to elevated blood glucose levels, but only when glucose is presentthis glucose-dependent mechanism reduces the risk of hypoglycaemia

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doi:10.1016/j.ceb.2011.08.004 105

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