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Transitioning between semaglutide and tirzepatide should therefore be supervised closely by a healthcare provider to minimize risks

Bkdal TA, Donsmark M, Hartoft-Nielsen M-L, Sndergaard FL, Connor A

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Other trials have supported the strategy of blocking mTOR/p70S6K as a method to control insulin action and potentially avoid upregulation of IGF-1R signaling by inhibition of mTOR
