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Furocoumarin derivatives increased the number of skin basal layer melanocytes and melanin-containing hair follicles, and upregulated melanin synthesis and TYR activity by activating cAMP/PKA and MAPK signalling pathways [268]
The Controversy Around Glutathione Whitening While glutathiones antioxidant benefits are well-established, the skin whitening aspect remains debated in the medical community
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Isopropyl -d-1-thiogalactopyranoside (IPTG) was added to a final concentration of 1 mM and the culture was further incubated at 18 C overnight
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