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GLP-1RA Lipid-Specific Outcomes While the GLP-1RAs used for weight loss, semaglutide and tirzepatide, have garnered much focus, multiple other GLP-1RA medications have shown positive outcomes on lipid profiles: dulaglutide has shown reduction in total cholesterol and LDL-C [65], liraglutide has shown reduction in LDL-C and ApoCIII [66], and exenatide has shown reduction in LDL-C and total cholesterol and increase in HDL-C [67]
Some of these patients also have macular pigmentation of the oral mucosa, especially on the lips, as a result of melanin deposition
This cascade induces smooth muscle relaxation and reduces phasic contractions, thus leading to a delay in gastric emptying [9]
Nausea and loss of appetite are commonespecially when the dosage is increased too quicklywhich can cause people to eat less without recognizing theyre at risk for malnutrition
Natural GH secretion occurs in discrete pulses rather than continuous elevation
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