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MAPK14/p38-dependent modulation of glucose metabolism affects ROS levels and autophagy during starvation
While gastrointestinal side effects like nausea and diarrhea are common with this GLP-1 receptor agonist, colitisinflammation of the colonhas not been established as a recognized adverse effect in FDA labeling or major clinical trials
Los estudios in vitro y en modelos animales han revelado que su mecanismo de accin no depende de un solo receptor, sino de una cascada de sealizacin intracelular compleja
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