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What the Current Clinical Evidence Shows Phase 2 trial data published in the NEJM in 2023 show gastrointestinal events including nausea were the most common side effects, were transient and self-limiting in most participants, and were more frequent at higher doses

In preclinical work, BPC157 has been evaluated in cellbased and animal models where investigators examine structural integrity, barrier function, and responses to experimental tissue injury, strictly within controlled research settings

The sensitivity analysis excluding one trial with a short duration and one trial that recruited participants on background insulin therapy yielded similar results and reduced statistical heterogeneity

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