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Read more: Thinking about bariatric surgery for weight loss

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Where appetite is the dominant driver of weight: the GLP-1/GIP dual mechanism of tirzepatide already addresses appetite and satiety powerfully, and adding a third receptor may offer diminishing marginal benefit for this specific lever

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Nature 459 , 663667 (2009)

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"Normal" eating on GLP-1 is eating smarter , not eating the same way with less appetite

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Missing one dose is unlikely to cause serious harm, but it can set back your momentum

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