[33, 34, 35, 36] Mechanism: Typically pre-renal, occurring in the setting of volume depletion from GI losses (nausea, vomiting, diarrhea, reduced oral intake) More frequently seen at higher, obesity-level doses Although generally reno-protective long term, post-marketing data describe acute rises in creatinine following days to weeks of significant GI symptoms Risk factors: Underlying chronic kidney disease Concomitant use of ACE inhibitors, ARBs, diuretics, or SGLT2 inhibitors ED Management: IV fluids Hold GLP-1 and contributing medications Usually reversible with supportive care Future Directions GLP-1 receptor agonists are rapidly evolving beyond their original indications in diabetes and obesity
Faster recovery from injuries
Divided by 5,000 mcg/mL, the draw is 0.08 mL or 8 units on a U-100 insulin syringe
Many people rush this step, and the result is a reaction they attribute to the medication itself rather than the alcohol contamination
Gke R, Larsen PJ, Mikkelsen JD, Sheikh SP