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Cardiovascular Outcomes with Once-Weekly GLP-1 RAs: Clinical and Economic Implications
Response times depend on the program and other factors
They do not rule out gallstones, gastroparesis, retinopathy, allergic reactions, bowel problems, or every potential medication complication
Some studies suggest that very high caffeine intake might slightly interfere with the absorption of certain nutrients
In the LEADER (liraglutide) and SUSTAIN-6 (semaglutide) trials [2, 3], the GLP-1RAs rapidly and greatly decreased HbA 1c levels compared to placebo, which may have partly contributed to the increased incidence of diabetic retinopathy complications observed in SUSTAIN-6 (HR: 1.76 [95% CI 1.11, 2.78])
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