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Then, we summarize clinical data from postmarketting surveillance, randomized controlled trials, and observational studies

The phosphorylated form of NAD + , NADP/NADPH, parallels NAD + /NADH by functioning as a redox coenzyme in the pentose phosphate pathway, generation of acetyl coenzyme A (acetyl-CoA) for lipid and cholesterol biosynthesis, and in the glutathione and thioredoxin antioxidant systems 4,5,8,9

doi: 10.1056/NEJMoa2028395 203 LoombaRHartmanMLLawitzEJVuppalanchiRBoursierJBugianesiEet al

Lancet 2019 , 394 , 121130

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