It confirmed ferroptosis as the core mechanism in PD pathogenesis synergistically induced by iron overload and inflammation, which activate ferroptosis by disrupting iron metabolism, inhibiting the antioxidant system and exacerbating lipid peroxidation, further causing dopaminergic neuronal damage, -syn aggregation, and PD-characteristic motor/cognitive impairments (186).Treating SH-SY5Y dopamine neurons with rotenone and using RhoNox-1 staining, followed by confocal microscopy observation and flow cytometry analysis, revealed significantly higher intracellular Fe 2+ in the rotenone group, confirming cellular iron overload (187)
Vitamin B12 shots are administered most often in those with genetic conditions that block absorption and people with the disorder called pernicious anemia, which can result in severe malabsorption and deficiency
GLP-1 medications such as Ozempic, Wegovy, and Mounjaro primarily work by reducing appetite, slowing stomach emptying, and improving blood sugar regulation
Reconstituted GHK-Cu is an intense blue from the copper-peptide complex
In the search to find new skin-lightening products, glutathione has come up as one of the most recent & popular molecule