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W., Bartke, A
Canfosfamide Canfosfamide, also known as TLK286, is a GSH analogue activated by GSTP1-1 into a GSH derivative and phosphorodiaminate, an alkylating metabolite that forms covalent linkages with DNA (Fig
NO can react with the cysteine of GSH to form GSNO that may be considered an endogenous NO reservoir, which can release it when it reacts with Cu + or with denitrosylating enzymes such as Trx and GSNO reductase (Sengupta and Holmgren, 2013)
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