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Many patients wonder whether taking their weekly shot on an empty stomach improves effectiveness or reduces nauseabut the clinical evidence provides clear guidance on this common concern

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Serious but rare adverse effects include: Acute pancreatitis (patients should be advised to seek immediate medical attention for severe, persistent abdominal pain) Gallbladder disease, including cholecystitis and cholelithiasis Acute kidney injury, particularly in the context of dehydration from gastrointestinal side effects Hypoglycaemia, especially when used alongside other glucose-lowering medications Thyroid C-cell tumours (observed in rodent studies

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Optional bedtime casein shake with 25 grams if total intake is still below target