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GLP-1s can make that harder, because, just as they suppress appetite, they dial back your sense of thirst

Stephanie Weiss, M.D., Ph.D., assistant director for the Clinical Research, Medication Development Program at NIDA, shared data from the first published clinical trial of GLP-1 RAs in alcohol use disorder: in patients with obesity with a BMI over 30, exenatide reduced heavy drinking days by 23.6% and lowered total alcohol intake

To assess the robustness of our meta-analytic results and identify potential outlier studies, we conducted a leave-one-out sensitivity analysis