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That is the three legged stool of evidence based medicine

Quick Answer: Weight loss injections do not directly impair fertility and may improve conception potential through metabolic optimization, but require discontinuation before planned pregnancy due to potential fetal risks

The choice depends on the cause of thrombocytopenia, patient preferences, and cost

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Both wanting and liking absent no enjoyment of anything, even normally loved activities is the pattern that warrants clinical evaluation for depression independent of the medication